The UK charity for WM & LPL – a rare type of blood cancer

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A Guide to Treatments for Waldenstrom's Macroglobulinaemia and Lymphoplasmacytic Lymphoma

September 24, 2026

Free guide to treatments for Waldenstrom's macroglobulinaemia (WM) and lymphoplasmacytic lymphoma (LPL), from active monitoring to chemo-immunotherapy.

This free guide is for people living with Waldenstrom’s macroglobulinaemia (WM) and lymphoplasmacytic lymphoma (LPL), and for their family and friends. WM and LPL are rare, slow-growing types of blood cancer. The guide explains the treatment options used in the UK, from active monitoring (watch and wait) through to chemotherapy, immunotherapy, targeted drugs and newer approaches. It also explains how to prepare for treatment and what to expect from it.

It also offers practical advice on managing side effects, keeping well during treatment, taking part in clinical trials for WM & LPL, and finding support. WMUK wrote the guide with expert healthcare professionals and people living with WM and LPL.

Published September 2026. Due for review September 2028.

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WM and LPL: A Guide to Treatments
Free guide to treatments for Waldenstrom’s macroglobulinaemia (WM) and lymphoplasmacytic lymphoma (LPL), from active monitoring to chemo-immunotherapy.
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