The UK charity for Waldenstrom’s macroglobulinaemia – a rare type of blood cancer
Support Line: 0300 373 8500

What are Checkpoint inhibitors

Checkpoint inhibitors

T-cells play a big role in your immune system, seeking out and fighting cells causing damage. WM cells use a protein to ‘hide’ from the T-cells so they aren’t attacked. Checkpoint inhibitors target these proteins, helping your T-cells to find and attack the WM cells.

These drugs aren’t available to people with WM, but you may hear of the following medicines which are being studied:

  • Nivolumab
  • Pembrolizumab

With a diagnosis of Waldenstrom’s macroglobulinaemia, you may be coming across new and unfamiliar words. Look them up in our WM glossary below.