The UK charity for Waldenstrom’s macroglobulinaemia – a rare type of blood cancer
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What is Cyclophosphamide?

Cyclophosphamide

Cyclophosphamide is a chemotherapy drug that can either be taken as a tablet or intravenously. This is often given alongside rituximab and a steroid called dexamethasone in a regimen commonly known as DRC. Like BR, DRC is another recommended regimen for people with Waldenstrom’s macroglobulinaemia, and has shown to be a less toxic form of treatment. It is usually given for up to 6 chemotherapy cycles. One cycle may last 3-4 weeks.

Dexamethasone can affect sleep with many people struggling to get to sleep for the day they have it. Dexamethasone can also affect your mood, often positively but sometimes negatively too.

Cyclophosphamide is also used in a regimen known as R-CHOP, which is often used to treat faster-growing forms of lymphoma.

Also see: Bendamustine

With a diagnosis of Waldenstrom’s macroglobulinaemia, you may be coming across new and unfamiliar words. Look them up in our WM glossary below.